Brain Training for TBI

LearningRx Research Bibliography

Posted by on Sep 22, 2019 in Brain Training for ADHD, Brain Training for Children & Adolescents, Brain Training for Seniors, Brain Training for TBI | Comments Off on LearningRx Research Bibliography

LearningRx Brain Training Research Studies Here is the most recent bibliography of LearningRx research: Carpenter, D., Ledbetter, C., & Moore, A.L. (2016). LearningRx cognitive training effects in children ages 8-14: A randomized controlled study. Applied Cognitive Psychology, 30(5), 815-826. doi: 10.1002/acp.3257. Retrieved from https://onlinelibrary.wiley.com/doi/full/10.1002/acp.3257 Gibson, K., Carpenter, D.M., Moore, A.L., & Mitchell, T. (2015). Training the brain to learn: Beyond vision therapy. Vision Development and Rehabilitation, 1(2), 120-129. Retrieved from https://www.covd.org/page/VDR_1_2 Hill, O.W., Zewelanji, S., & Faison, O. (2016). The Efficacy of the LearningRx Cognitive Training Program: Modality and Transfer Effects. Journal of Experimental Education: Learning, Instruction, and Cognition, 84(3), 600-620. doi: 10.1080/00220973.2015.1065218. Jedlicka, E. (2017). LearningRx cognitive training for children and adolescents ages 5-18: Effects on academic skills, behavior, and cognition. Frontiers in Education, 2(62). doi: 10.3389/feduc.2017.00062. Retrieved from https://www.frontiersin.org/articles/10.3389/feduc.2017.00062/full   Ishanpara, P. D. (2013). Cognitive rehabilitation with LearningRx: Preliminary improvements in memory after traumatic brain injury. Retrieved from ProQuest Dissertations and Theses. UMI No. 3574228 James, R., Moore, A.L., Carpenter, D., Miller, T., & Ledbetter, C. (2019). Feasibility of a Functional Medicine Approach to Slowing Clinical Cognitive Decline in Patients Over Age 55: A Multiple Case Study Report. OBM Integrative and Complementary Medicine, 4(3). doi: 10.21926/obm.icm.1903054 https://www.gibsonresearchinstitute.org/wp-content/uploads/2019/09/MCI-Intervention_James-et-al.pdf Ledbetter, C., Moore, A.L., Mitchell, T. (2017). Cognitive effects of ThinkRx cognitive rehabilitation training for eleven soldiers with brain injury: A retrospective chart review. Frontiers in Psychology, 8(825). doi: 10.3389/fpsyg.2017.00825. Retrieved from https://www.frontiersin.org/articles/10.3389/fpsyg.2017.00825/full Ledbetter, C., & Moore, A. (2018). Neuroimaging outcomes of a cognitive rehabilitation training program. Journal of Neuroimaging, 28(2), 225-233. doi: 10.1111/jon.12507. Retrieved from https://www.gibsonresearchinstitute.org/wp-content/uploads/2018/03/Neuroimaging-Outcomes-of-a-Cognitive-Rehabilitation-Training-Program_-J-of-Neuroimaging-excerpt.pdf Ledbetter, C., Faison, M.O., & Patterson, J. (2016). Correlation of cognitive training gains and resting state functional connectivity. Presented at Society for Neuroscience, November 2016, San Diego, CA. Retrieved from https://www.gibsonresearchinstitute.org/wp-content/uploads/2016/11/SFNposters_CLedbetter.pdf Luckey, A. J. (2009). Cognitive and academic gains as a result of cognitive training. Retrieved from ProQuest Dissertations and Theses. UMI No. 3391981 Moore, A.L., Carpenter, D.M., Ledbetter, C., & Miller, T.M. (2018). Clinician-delivered cognitive training for children with attention problems: Transfer effects on cognitive and behavior from the ThinkRx randomized controlled trial. Neuropsychiatric Disease and Treatment, 14, 1671-1683. doi: 10.2147/NDT.S165418. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027847/ Moore, A.L., Carpenter, D.M., Miller, T.M., & Ledbetter, C., (2019). ThinkRx Cognitive Training for Adults over Age 50: Clinician-Caregiver Partners in Delivery as Effective as Clinician-Only Delivery. Psychology and Neuroscience, 12(2), 291-306. doi: 10.1037/pne0000162. Author’s copy available at https://www.gibsonresearchinstitute.org/wp-content/uploads/2019/02/ThinkRx-for-Adults-Over-50_Psy-and-Neuroscience_2019.pdf Moore, A.L., Carpenter, D.M., Miller, T.M., & Ledbetter, C. (2019). Comparing Two Methods of Delivering ThinkRx Cognitive Training to Children Ages 8-14: A Randomized Controlled Trial of Equivalency. Journal of Cognitive Enhancement, 3(3), 261-270. doi.org/10.1007/s41465-018-0094-z. Retrieved from https://link.springer.com/article/10.1007/s41465-018-0094-z Moore, A.L., & Ledbetter, C. (2019). The Promise of Clinician-Delivered Cognitive Training for Children Diagnosed with ADHD. Journal of Mental Health and Clinical Psychology, 3(3), 3-8. doi: 10.29245/2578-2959/2019/3.1180. Retrieved from https://www.mentalhealthjournal.org/articles/the-promise-of-cliniciandelivered-cognitive-training-for-children-diagnosed-with-adhd.pdf Moore, A.L., & Miller, T. (2018). Reliability and validity of the revised Gibson Test of Cognitive Skills, a computer-based test battery for assessing cognition across the lifespan. Psychology Research and Behavior Management, 11, 25-35. doi:10.2147/PRBM.S152781. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813948/ Moore, A.L., James, R., Carpenter, D., Miller, T., & Ledbetter, C. (2018). MRI and Neuropsychological Outcomes following a Functional Medicine Intervention with Cognitive Training in Mild Cognitive Impairment (MCI): A Multiple Case Study. Presentation at American Psychological Association Annual Convention, August 2018, San Francisco, CA. Retrieved from https://www.gibsonresearchinstitute.org/wp-content/uploads/2019/01/2018-APA_MCI-Poster_Moore-et-al.pdf Moore, A.L., & Ledbetter, C. (2018). MRI, qEEG, & neuropsychological outcomes following cognitive rehabilitation training for severe traumatic brain injury: A clinical case study. Presentation at Brain Injury Summit, Jan 2018, Vail, CO. Retrieved from https://www.gibsonresearchinstitute.org/wp-content/uploads/2018/01/2018-TBI-Summit-Presentation_MooreLedbetter_web.pdf Moore, A.L., Ledbetter, C., & Carpenter, D. (2017). MRI and neuropsychological outcomes following cognitive rehabilitation training in traumatic...

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LearningRx Research: Brain Training for Traumatic Brain Injury

Posted by on Jun 22, 2018 in Brain Training for TBI | Comments Off on LearningRx Research: Brain Training for Traumatic Brain Injury

Here’s a selection of research on LearningRx brain training for traumatic brain injury (TBI): Ledbetter, C., Moore, A.L., Mitchell, T. (2017). Cognitive effects of ThinkRx cognitive rehabilitation training for eleven soldiers with brain injury: A retrospective chart review. Frontiers in Psychology, 8(825). doi: 10.3389/fpsyg.2017.00825 The current study examined the cognitive outcomes following ThinkRx, a clinician-delivered cognitive rehabilitation training program for soldiers recovering from traumatic brain injury (TBI) and acquired brain injury (ABI). In a retrospective chart review, we examined cognitive outcomes of 11 cases who had completed an average of 80 hours of ThinkRx cognitive rehabilitation training delivered by clinicians and supplemented with digital training exercises. Outcome measures included scores from six cognitive skill batteries on the Woodcock Johnson  III Tests of Cognitive Abilities. Participants achieved gains in all cognitive skills tested and achieved statistically significant changes in long-term memory, processing speed, auditory processing, and fluid reasoning with very large effect sizes. Clinically significant changes in multiple cognitive skills were also noted across cases. Link to article: http://journal.frontiersin.org/article/10.3389/fpsyg.2017.00825/full   Ledbetter, C., & Moore, A. (2018). Neuroimaging outcomes of a cognitive rehabilitation training program. Journal of Neuroimaging, 28(2), 225-233. doi: 10.1111/jon.12507 To investigate if aberrant brain connectivity and changes in brain connectivity (a neuroimaging marker of neuroplasticity), were evident prior to and after completion of a robust cognitive training program, a series of case studies were carried out in subjects with varying degrees of traumatic brain injuries (n = 5) and cognitive impairment (n = 5). MR exams were acquired on all subjects prior to and upon completion of the ThinkRx cognitive training program. In addition to MR exams, all subjects completed pre-post neuropsychological testing (WJ-IV) and condition-specific rating scales. For all cases, neuropsychological testing and qualitative outcomes measures increased, supporting that the robustness of the training program held for each imaged case study. Normalization of DMN connectivity, including decreased hyperconnectivity and reoccurrence of anticorrelated activity, was evident in the most severe TBI case. At the group level, significant training-induced changes in neural connectivity were identified.  Read the article. Or read the abstract on pages 230-231:Neuroimaging Outcomes for TBI and MCI_J of Neuroimaging   Moore, A.L., & Ledbetter, C. (2018). MRI, qEEG, & neuropsychological outcomes following cognitive rehabilitation training for severe traumatic brain injury: A clinical case study. Presentation at Brain Injury Summit, Jan 2018, Vail, CO. Using a single case design, we examined neural connectivity changes with fMRI, qEEG, and changes in IQ score, working memory, long-term memory, visual & auditory processing, processing speed, attention, reasoning, and everyday functioning following 60 hours of cognitive training 8 years after a severe Traumatic Brain Injury.  Neuropsychological testing results showed a 21-point increase in IQ score and significant gains in working memory, processing speed, logic and reasoning, and visual processing; as well as gains in long-term memory and auditory processing.  FMRI showed normalization of the Default Mode Network (DMN) with reappearance of anti-correlations, and decreased hyperconnectivity was evident post-training.  Post qEEG showed normalization of activity in the left frontal region which was previously abnormal.  Functional outcomes included improved motivation for life, better focus and problem-solving, improved mood, no deficits in daily living tasks, and a return to former high level career field. Link to presentation   Moore, A.L., Ledbetter, C., & Carpenter, D. (2017). MRI and neuropsychological outcomes following cognitive rehabilitation training in traumatic brain injury: A Multiple case study.  Presented at Society for Neuroscience, November 2017, Washington, DC. Using a multiple case study design, we examined neural connectivity changes with fMRI and changes in IQ score, working memory, long-term memory, visual & auditory processing, processing speed, attention, reasoning, and everyday functioning...

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